Gerald E. Duhamel
Professor
Research Focus
- The long-range goal is to define basic mechanisms of host-parasite interactions, and their relationship to susceptibility or resistance against diseases, particularly within the framework of enteric bacterial infections in animal models of human diseases. Presently, we are engaged in basic and applied biomedical research aimed at characterizing the molecular basis of microbial pathogenesis and host defense with practical applications to diagnosis and control of enteric diseases of animals and human beings. Specifically, we are investigating molecular mechanisms of bacterial virulence and host-pathogen interactions in cultured cell and laboratory mice and non-human primate animal models, phenotypic and genotypic bases of microbial diversity, and functional genomics of polymicrobial infections of the colon.
