Paula Cohen
Associate Professor
Research Focus
- Role of the DNA mismatch repair (MMR) family in mammalian meiosis and recombination.
- Analysis of MMR mouse mutants and their subsequent meiotic phenotypes
- Identification of key protein-protein and protein-DNA interactions during mouse meiosis in order to understand how recombination events are regulated, monitored and resolved
- Human female meiosis at the molecular level
- Human oocytes after meiotic recombination events have been resolved
- Genetic/environmental influences on recombination proficiency in human oocytes
Research Grants
- MECHANISMS OF MISMATCH REPAIR PROTEIN FUNCTION IN THE PATHOGENESIS OF HUNTINGTON'S DISEASE: FELLOW: DR. JOANNA KIM HOLLOWAY
- ELUCIDATING THE FUNCTIONAL RELATIONSHIP BETWEEN NEK1 AND FKBP6 IN MAMMALIAN MEIOSIS
- THE MLH1-MLH3 HETERODIMER IN MAMMALIAN MEIOTIC RECOMBINATION AND GAMETOGENESIS
- MAMMALIAN DNA REPAIR PROTEINS IN MEIOTIC RECOMBINATION
