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Antje J Baeumner

Professor

Primary Research Areas

  • biomedical instrumentation and diagnostics
  • food science
  • genomics
  • materials science
  • nanobiotechnology
  • nanomaterials, nanodevices, and nanoscience
  • pathogens
  • science education

Graduate Fields

Research Focus

The research is focused on the development of bioanalytical detection tools. Research is in part applied, i.e. focusing on solving a specific problem important to the safety of humans or animals, and for clinical diagnostics. This includes research toward the design and prototyping of sensors for the use in resource-limited settings, such as Sub-Saharan Africa. Other parts are involved with more basic research toward the development of bioanalytical tools. Biochemical, microbiological and nanofabrication research is being used to reach these goals.

Educational Background

  • Ph.D., Universität Stuttgart: Technical Biochemistry, 1997
  • M.S., Technische Universität Braunschweig: Biotechnology, 1994

Research Grants

  • CRYPTOSPORIDIUM PARVUM BIOSENSOR FOR DRINKING WATER SAFETY
  • DEVELOPMENT OF A LIPOSOME-BASED CD4+ T-CELL BIOSENSOR

Selected Publications

PubMed Listings
  • Nugen, S.R., Leonard, B., Baeumner, A.J. “Application of a unique server-based oligonucleotide probe selection tool toward a novel biosensor for the detection of Streptococcus pyogenes” Biosensors and Bioelectronics (available online, 11/29/2006))
  • Katie A. Edwards, Antje J. Baeumner “Synthesis of a liposome incorporated 1-carboxyalkylxanthine-phospholipid conjugate and its recognition by an RNA aptamer” Talanta, vol 71(1) pp. 365 – 372 (2007), doi:10.1016/j.talanta.2006.04.031
  • Edwards, K.A. and Baeumner, A.J. “Optimization of DNA-tagged Dye- Encapsulating Liposomes for Lateral-Flow Assays Based on Sandwich-Hybridization” Analytical and Bioanalytical Chemistry vol. 386 (5), pp. 1335 – 1343 (2006) (http://dx.doi.org/10.1007/s00216-006-0705-x)
  • Edwards, K.A. and Baeumner, A.J. “Optimization of DNA-tagged Liposomes for Use in Microtiter Plate Analyses” Analytical and Bioanalytical Chemistry, vol. 386 (6), pp. 1613 – 1623 (2006) (doi: 10.1007/s00216-006-0743-4)
  • Li, Dapeng; Frey, Margaret W.; Baeumner, Antje J. Electrospun polylactic acid nanofiber membranes as substrates for biosensor assemblies. Journal of Membrane Science (2006), 279(1-2), 354-363.
  • Vasiliy N. Goral, Natalya V. Zaytseva, Antje J. Baeumner “Electrochemical microfluidic biosensor for the detection of nucleic acid sequences” Lab-on-Chip, vol 6(3), pp. 414 - 421 (2006) DOI 10.1039/b513239h
  • Katie A. Edwards and Antje J. Baeumner “A Sequential Injection Analysis System for the Sandwich-Hybridization-Based Detection of Nucleic Acids” Analytical Chemistry,vol. 78 (6), pp. 1958-1966 (2006)
  • Sylvia Kwakye, Vasiliy N. Goral and Antje J. Baeumner “Electrochemical microfluidic biosensor for nucleic acid detection with integrated minipotentiostat.” Biosensors and Bioelectronics, vol. 21, pp. 2217 – 223 (2006)
  • Kevin P. Nichols, Julia R. Ferullo, Antje J. Baeumner “Recirculating Microfluidic Mixer” Lab-on-Chip, vol. 6(2) pp. 242 - 246 (2006)
  • Katie A. Edwards, Harriet A. Clancy and Antje J. Baeumner “Bacillus anthracis: Toxicology, Epidemiology and Current Detection Methods” Analytical and Bioanalytical Chemistry., vol. 384, pp. 73-84 (2006)
  • Katie A. Edwards and Antje J. Baeumner “Analysis of Liposomes” Talanta, vol. 68 (5) pp. 1432-1441 (2006)
  • Katie A. Edwards and Antje J. Baeumner “Liposomes in Analysis” Talanta, vol. 68 (5) pp. 1421-1431 (2006)
  • Natalya V. Zaytseva, Richard A. Montagna, and Antje J. Baeumner “Microfluidic biosensor for the serotype-specific detection of Dengue virus” Analytical Chemistry, vol. 77, p. 7520 – 7527 (2005)
  • Natalya V. Zaytseva, Vasiliy N. Goral, Richard A. Montagna, and Antje J. Baeumner “Development of a microfluidic biosensor module for pathogen detection” Lab-on-chip, vol 5 (8), pp. 805 – 811 (2005) (issue cover picture)
  • Hsiao-Wei Wen, · Wlodzimierz Borejsza-Wysocki, Thomas R. DeCory, Antje J. Baeumner Richard A. Durst, “A novel extraction method for peanut allergenic proteins in chocolate and their detection by a liposome-based lateral flow assay” European Food Research and Technology, vol. 221, pp. 564 – 569 (2005)
  • Chien-Sheng Chen, Antje J. Baeumner, Richard A. Durst “Protein G-liposomal nanovesicles as universal reagents for immunoassays” Talanta, vol. 67, pp. 205 – 211 (2005)
  • Antje Baeumner “Bioanalytical Microsystems: Technology and Applications” invited book chapter, chapter 6, pp. 251-284 “Biosensors and Modern Biospecific Analytical Techniques”, (Ed. L. Gorton), Vol. XLIV, Comprehensive Analytical Chemistry (Ser. Ed. D. Barcelo, Elsevier, Amsterdam, 2005. doi:10.1016/S0166-526X(05)44006-4
  • Antje J. Baeumner, Barbara Leonard, John McElwee, Richard A. Montagna “A Rapid Biosensor for Viable B. anthracis Spores” Analytical Bioanalytical Chemistry, vol. 380 (1), p. 15 – 23 (2004)
  • Natalya Zaytseva, Richard A. Montagna, Eun Mi Lee and Antje J. Baeumner “Multi-Analyte Single-Membrane Biosensor for Serotype Specific Detection of Dengue Virus” Analytical Bioanalytical Chemistry, vol. 380 (1), p. 46 – 53 (2004)
  • Antje J. Baeumner, Caroline Jones, Ching Yee Wong, and Andrew Price “A Generic Sandwich-type Biosensor with Nanomolar Detection Limits” Analytical and Bioanalytical Chemistry, vol. 378 (6), pp. 1587 – 1593 (2004)
  • A.J. Baeumner, J. Pretz, S. Fang “A Universal Nucleic Acid Sequence Biosensor with Nanomolar Detection Limits”, Analytical Chemistry, vol. 76 (4), pp. 888 – 894 (2004)
  • Antje Baeumner “Bioanalytical Microsystems: Technology and Applications” invited book chapter, Editor Lo Gorton (Elsevier) accepted in Oct. 2002
  • A.J. Baeumner “Biosensors for Environmental Pollutants and Food Contaminants” Analytical and Bioanalytical Chemistry, vol 377 (3), pp. 434 – 445, (2003) (invited review)
  • J.-H. Min and A.J. Baeumner “Characterization and Optimization of Interdigitated Ultramicroelectrode Arrays as Electrochemical Biosensor Transducers” Electroanalysis, May 2003 (published online, Feb. 20th, 2004)
  • S. Kwakye and A. Baeumner “A Microfluidic Biosensor Based on Nucleic Acid Sequence Recognition” Analytical and Bioanalytical Chemistry, vol. 376 (7), pp. 1062 – 1068 (2003)
  • A.J. Baeumner and R.A. Durst “Foreword: 5th Workshop on Biosensors and Biological Techniques in Environmental Analysis” Analytica Chimica Acta, vol. 487 (1), p. 1, 2003
  • H.A. Hartley and A.J. Baeumner “Biosensor for the Specific Detection of a Single Viable B. anthracis Spore” Analytical and Bioanalytical Chemistry, vol. 376 (3), pp. 319 – 327 (2003) (article published in category “Paper in Forefront”)
  • S. Ahn-Yoon, R.R. DeCory, A.J. Baeumner and R.A. Durst “Ganglioside-Liposome Immunoassay for the Ultrasensitive Detection of Cholera Toxin”, Analytical Chemistry, vol. 75, pp. 2256 – 2261 (2003)
  • J.-H. Min and A.J. Baeumner, “The micro-Total Analytical System for the Detection of Bacteria/Viruses” J. Industrial Engineering Chemistry, vol. 9 (1), pp. 1 – 8 (2003)
  • A.J. Baeumner, R.N. Cohen, V. Miksic, J.H. Min “RNA Biosensor for the Rapid Detection of Viable Escherichia coli in Drinking Water” Biosensors & Bioelectronics, vol. 8 (4) pp. 405 – 419 (2003)
  • M.D. Dhawan, F. Wise, A.J. Baeumner “Development of a Laser-Induced Cell Lysis System” Analytical and Bioanalytical Chemistry, vol. 374, pp. 421 – 426 (2002) 
  • A.J. Baeumner, N. A. Schlesinger, N. S. Slutzki, J. Romano, E.M. Lee, R.A. Montagna “A biosensor for Dengue Virus Detection: Sensitive, Rapid and Serotype specific” Analytical Chemistry, vol. 74 (6), p. 1442 – 1448 (2002)
  • J.-H. Min and A.J. Baeumner “Highly Sensitive and Specific Detection of Viable Escherichia coli in Drinking water” Analytical Biochemistry, vol. 303, p. 186 – 193 (2002)
  • M.B. Esch, A.J. Baeumner, R.A. Durst “Detection of Cryptosporidium parvum Using Oligonucleotide-Tagged Liposomes in a Competitive Assay Format “Analytical Chemistry vol. 73 (13), pp. 3162-3167 (2001)
  • A.J. Baeumner, M.C. Humiston, R.A. Montagna, R.A. Durst “Detection of Viable Oocysts of Cryptosporidium parvum Following Nucleic Acid Sequence-Based Amplification” Analytical Chemistry vol. 73 (6), pp. 1176-1180 (2001)
  • L. Mosiello, L. Segre, S. Chiavarini, C. Cremisini, M. Spano, A.J. Bäumner, T. Kimmel, R.D. Schmid “Dipstick Immunoassay Format for Atrazine and Terbutylazine Analysis in Water Samples.” J. Agricultural and Food Chemistry vol. 46 (9), 3847 - 3851, 1998
  • A.J. Bäumner and R.D. Schmid, “Development of a New Immunosensor for Pesticide Detection: a Disposable System with Liposome-Enhancement and Amperometric Detection” Biosensors & Bioelectronics vol. 13 (5), 519 - 529 (1998)
  • R.A. Durst, A.J. Bäumner, R.W. Murray, R.P. Buck, C.P. Andrieux, “Chemically Modified Electrodes: Recommended Terminology and Definitions” Pure & Applied Chemistry vol. 69 (6), pp. 1317 - 1323 (1997)
  • A.J. Bäumner, T. Kummer, R.D. Schmid, “Liposome-Based Immunosensors: 1. Influence of Hapten Spacer Length on Liposome Binding Efficiency.” Analytical Letters vol 29 (15), pp. 2601-2613 (1996)