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Yung-Fu Chang

Professor

Graduate Fields

Research Focus

  • Molecular biology of infectious disease
  • DNA and recombinant subunit vaccine development
  • Molecular basis of bacterial pathogenesis
  • Immunopathology of infectious disease
  • Molecular diagnosis of infectious diseases
  • Host defense mechanisms
  • Comparative genomics and proteomics

My research focuses on both basic and applied aspects.  My research interest is to understand the mechanisms of infection and concurrently develop an effective vaccine to prevent the infection of the pathogens such as M. avium subsp. paratubercuosis, Leptospira and Salmonella.

Educational Background

  • DVM, National Pingtung Institute of Agriculture, Taiwan, 1974
  • M.S., Immunology/Pathology, University of Idaho, 1981
  • Ph.D., Microbiology/Immunology, Texas A&M University, 1984

Research Grants

  • CORNELL ZRU PROJECT CONCEPT - MOLECULAR DIAGNOSIS OF BACTERIAL PATHOGENS
  • C. DIFFICILE: GENOMICS/TRANSCRIPTOME STUDY
  • ANTIGEN DELIVERY SYSTEM FOR ELICITATION OF PROTECTIVE IMMUNITY AGAINST JOHNE'S DISEASE.
  • IDENTIFICATION OF L. BORGPETERSENII SEROVAR HARDJO VIRULENCE FACTORS AND VACCINE DEVELOPMENT
  • PARATUBERCULOSIS: NOVEL DNA VACCINE WITH SINGLE CHAIN BOVINE IL-12 ADJUVANT
  • USING ATTENUATED SALMONELLA STRAINS FOR DELIVERY OF PROTECTIVE ANTIGENS OF MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS (MAP)