John D Helmann
Professor
Primary Research Areas
- biochemistry
- biogeochemistry
- bioinformatics
- genomics
- microbiology
- molecular biology
Research Focus
Our laboratory studies Bacillus subtilis, a Gram-positive soil bacterium and genetic model system. Major research efforts address the stress responses elicited by (i) antibiotics that affect the cell envelope, (ii) reactive oxygen species, or (iii) deficiency or excess of nutrient metal ions. For each stress response, we are interested in the global patterns of transcriptional control, the mechanisms of the corresponding regulatory proteins, and the roles of the induced pathways.
Educational Background
- B.S., Chemistry and Biology, University of California, Santa Cruz, 1982
- Ph.D., Biochemistry, University of California, Berkeley, 1987
Research Grants
- GENE REGULATION BY OXIDATIVE STRESS IN BASILLUS SUBTILIS
- METAL ION HOMEOSTASIS IN BACILLUS SUBTILIS
- ECF SIGMA FACTORS AND CELL ENVELOPE STRESS IN BACILLUS SUBTILIS
