Eric Young Denkers
Professor
Graduate Fields
Research Focus
Basis of host immunity to microbial pathogens
Cellular and molecular responses to the opportunistic protozoan parasite, Toxoplasma gondii, using the mouse as an experimental model
Dissecting early events involved in immunity to this parasite
- Role of neutrophils during toxoplasmosis
- Polymorphonuclear leukocytes (PMN) in establishment of immunity to microbial infection
- Effects of PMN depletion on the immune response in mice
- Examining neutrophil interactions with other cells of the immune system
- Spectrum of cytokines released by PMN during infection
- Host intracellular signaling pathways during Toxoplasma infection
- How intracellular signaling cascades within the host cell are influenced by the presence of an ongoing infection
- Determining which signaling pathways are activated, and which may be disabled, by intracellular infection
Educational Background
- BS, Biology, University of Washington, 1982
- PhD, Molecular Biology, University of Wisconsin-Madison, 1990
Research Grants
- IMMUNOBIOLOGY OF PARASITIC DISEASES
- SIGNAL TRANSDUCTION DURING TOXOPLASMA INFECTION
- ROLE OF CCL2/MCP-1 IN MUCOSAL IMMUNITY TO TOXOPLASMA
- SIGNAL TRANSDUCTION DURING TOXOPLASMA INFECTION
- ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
